methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

Base Information

Chemical Name:methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate
CAS No.:1415657-67-8
Molecular Formula:C₂₀H₃₀N₂O₆
Molecular Weight:394.468
Hs Code.:

Synonyms:methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

Suppliers and Price of methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

There total 1 articles about methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 75178-96-0
N-Boc-1,3-diaminopropane

: 119-84-6,1341-36-2
C₆H₄(CH₂CH₂C(O)O)

: 96-32-2
bromoacetic acid methyl ester

: 1415657-67-8
methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

Guidance literature:: N-Boc-1,3-diaminopropane; C₆H₄(CH₂CH₂C(O)O); In acetonitrile; at 20 ℃; for 16h;

bromoacetic acid methyl ester; With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 2h;
DOI:10.1021/jo302089f

Reference yield:

: 1415657-67-8
methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

: C₁₉H₂₈N₂O₆

Guidance literature:: With lithium hydroxide monohydrate; In methanol; water; at 20 ℃; for 3h;
DOI:10.1021/jo302089f

Reference yield:

: 1415657-67-8
methyl 2-(2-(3-((3-((tert-butoxycarbonyl)amino)propyl)amino)-3-oxopropyl)phenoxy)acetate

: 1415657-69-0
N-(3-(3-(2-(2-((2-(1H-imidazol-4-yl)ethyl)amino)-2-oxoethoxy)phenyl)propanamido)propyl)-3-iodobenzamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium hydroxide monohydrate / methanol; water / 3 h / 20 °C

2.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide; dichloromethane / 0.25 h / 20 °C

2.2: 18 h / 20 °C

3.1: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

4.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 6 h / 20 °C

With hydrogenchloride; lithium hydroxide monohydrate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo302089f