(1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone

Base Information

• Chemical Name: (1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone
• CAS No.: 797791-51-6
• Molecular Formula: C₁₅H₂₁NO₂
• Molecular Weight: 247.337
• Mol file: 797791-51-6.mol

Synonyms:(1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone

Chemical Property of (1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone

Chemical Property:

Purity/Quality:

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• Hazard Codes: 

MSDS Files:

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Technology Process of (1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone

There total 1 articles about (1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

allyl bromide (106-95-6) + (2-methoxyphenyl)(pyrrolidin-1-yl)methanone (120173-04-8) → (1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone (797791-51-6)

Guidance literature:

(2-methoxyphenyl)(pyrrolidin-1-yl)methanone; With ammonia; potassium; tert-butyl alcohol; In tetrahydrofuran;

allyl bromide; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2004.09.025

Reference yield: 80.0%

(1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone (797791-51-6) → 4-methyl-2-allyl-2-(N-pyrrolidinyl)-carboxamide-3-cyclohexenone

Guidance literature:

With hydrogenchloride; methanol;

DOI:10.1016/j.tetlet.2004.09.025

Reference yield:

(1-allyl-2-methoxy-cyclohexa-2,5-dienyl)-pyrrolidin-1-yl-methanone (797791-51-6) → 4-methyl-4-allyl-2-(N-pyrrolidinyl)-carboxamide-2-cyclohexenone

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / HCl; MeOH

2: 62 percent / 1,2-dichlorobenzene / Heating

With hydrogenchloride; methanol; 1,2-dichloro-benzene; 2: Cope rearrangement;

DOI:10.1016/j.tetlet.2004.09.025

upstream raw materials:

allyl bromide

(2-methoxyphenyl)(pyrrolidin-1-yl)methanone