N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide
CAS No.:1609064-40-5
Molecular Formula:C₁₈H₁₉FN₂O₂S
Molecular Weight:346.425
Hs Code.:

Synonyms:N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Suppliers and Price of N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

There total 6 articles about N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 92206-38-7
ammonium acetate

: 399-51-9
6-fluoro-1H-indole

: 75-52-5
nitromethane

: 121-44-8
triethylamine

: 98-59-9
p-toluenesulfonyl chloride

: 74-88-4
methyl iodide

: 1609064-40-5
N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Guidance literature:: 6-fluoro-1H-indole; methyl iodide; With potassium hydroxide; In N,N-dimethyl-formamide;

With trichlorophosphate; In N,N-dimethyl-formamide;

ammonium acetate; nitromethane; triethylamine; p-toluenesulfonyl chloride; Further stages;
DOI:10.1039/c9cc08646c

Reference yield:

: C₁₁H₁₃FN₂

: 98-59-9
p-toluenesulfonyl chloride

: 1609064-40-5
N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.tet.2015.05.065

Reference yield:

: 441715-93-1
6-fluoro-1-methyl-1H-indole-3-carbaldehyde

: 1609064-40-5
N-(2-(6-fluoro-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium acetate / 1 h / Reflux; Inert atmosphere

2: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / Reflux; Inert atmosphere

3: triethylamine / dichloromethane / 0 - 20 °C

With lithium aluminium tetrahydride; ammonium acetate; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2015.05.065