Fmoc-PheΨ(COO)Leu-NH2

Base Information

Chemical Name:Fmoc-PheΨ(COO)Leu-NH2
CAS No.:1005343-30-5
Molecular Formula:C₃₀H₃₂N₂O₅
Molecular Weight:500.594
Hs Code.:

Synonyms:Fmoc-PheΨ(COO)Leu-NH2

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Chemical Property of Fmoc-PheΨ(COO)Leu-NH2

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Technology Process of Fmoc-PheΨ(COO)Leu-NH2

There total 1 articles about Fmoc-PheΨ(COO)Leu-NH2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 13748-90-8,498-36-2
(S)-2-hydroxyl-3,3-dimethylbutyric acid

: 35661-40-6
N-Fmoc L-Phe

: 1005343-30-5
Fmoc-PheΨ(COO)Leu-NH2

Guidance literature:: (S)-2-hydroxyl-3,3-dimethylbutyric acid; With benzotriazol-1-ol; Rink amide MBHA resin; diisopropyl-carbodiimide; microwave iradiation;

N-Fmoc L-Phe; With dmap; N-Ethylmaleimide; diisopropyl-carbodiimide; In N,N-dimethyl-formamide; at 90 ℃; for 0.2h; microwave irradiation;

With trifluoroacetic acid; at 20 ℃; for 4h; Further stages.;
DOI:10.1016/j.tetlet.2007.11.004