(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

Base Information

Chemical Name:(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester
CAS No.:1037367-36-4
Molecular Formula:C₁₉H₂₃NO₄
Molecular Weight:329.396
Hs Code.:

Synonyms:(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

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Chemical Property of (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

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Technology Process of (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

There total 1 articles about (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1037367-35-3
(1S,5S)-3-[(1S)-1-phenylethyl]-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

: 501-53-1,94274-21-2
benzyl chloroformate

: 1037367-36-4
(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

Guidance literature:: In dichloromethane; at 20 ℃; for 16h;

Reference yield:

: 1037367-36-4
(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

: 1037367-38-6
(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid

Guidance literature:: (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester; With sodium hydroxide; water; In tetrahydrofuran; ethanol; at 20 ℃; for 1h;

With hydrogenchloride; water; In tetrahydrofuran; ethanol;