(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid

Base Information

Chemical Name:(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid
CAS No.:1037367-38-6
Molecular Formula:C₁₇H₁₉NO₄
Molecular Weight:301.342
Hs Code.:

Synonyms:(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid

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Chemical Property of (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid

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Technology Process of (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid

There total 1 articles about (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1037367-36-4
(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester

: 1037367-38-6
(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid

Guidance literature:: (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid ethyl ester; With sodium hydroxide; water; In tetrahydrofuran; ethanol; at 20 ℃; for 1h;

With hydrogenchloride; water; In tetrahydrofuran; ethanol;

Reference yield:

: 1037367-38-6
(1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid

: 75-65-0
tert-butyl alcohol

: 1037367-37-5
(1S,5R)-3-benzyloxycarbonyl-1-(tert-butoxycarbonylamino)-6-spirocyclopropane-3-azabicyclo[3.2.0]heptane

Guidance literature:: (1S,5S)-3-benzyloxycarbonyl-6-spirocyclopropane-3-azabicyclo[3.2.0]heptan-1-ylcarboxylic acid; With diphenyl phosphoryl azide; triethylamine; In toluene; at 20 - 90 ℃; for 0.75h;

tert-butyl alcohol; In toluene; at 120 ℃; for 6h;