Technology Process of 3-benzyl-2,4-bis((trimethylsilyl)oxy)-1-butene
There total 5 articles about 3-benzyl-2,4-bis((trimethylsilyl)oxy)-1-butene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 96 percent / LiAlH4 / diethyl ether / 17 h / Ambient temperature
2: 85 percent / aq. oxalic acid, silica gel / CH2Cl2 / Ambient temperature
3: 1.) LDA / 1.) THF, hexane, a) -78 deg C, 15 min, b) 25 deg C, 15 min, 2.) RT, 15 min
With
lithium aluminium tetrahydride; oxalic acid; silica gel; lithium diisopropyl amide;
In
diethyl ether; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 85 percent / aq. oxalic acid, silica gel / CH2Cl2 / Ambient temperature
2: 1.) LDA / 1.) THF, hexane, a) -78 deg C, 15 min, b) 25 deg C, 15 min, 2.) RT, 15 min
With
oxalic acid; silica gel; lithium diisopropyl amide;
In
dichloromethane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) EtONa / 1.) EtOH, reflux, 30 min, 2.) reflux, 6 h
2: 93 percent / camphor sulphonic acid / benzene / 23 h / Heating
3: 96 percent / LiAlH4 / diethyl ether / 17 h / Ambient temperature
4: 85 percent / aq. oxalic acid, silica gel / CH2Cl2 / Ambient temperature
5: 1.) LDA / 1.) THF, hexane, a) -78 deg C, 15 min, b) 25 deg C, 15 min, 2.) RT, 15 min
With
lithium aluminium tetrahydride; camphor-10-sulfonic acid; sodium ethanolate; oxalic acid; silica gel; lithium diisopropyl amide;
In
diethyl ether; dichloromethane; benzene;
