C₃₄H₆₆O₄Si₂

Base Information

• Chemical Name: C₃₄H₆₆O₄Si₂
• CAS No.: 1289377-53-2
• Molecular Formula: C₃₄H₆₆O₄Si₂
• Molecular Weight: 595.067
• Mol file: 1289377-53-2.mol

Synonyms:C₃₄H₆₆O₄Si₂

Chemical Property of C₃₄H₆₆O₄Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₆₆O₄Si₂

There total 10 articles about C₃₄H₆₆O₄Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C22H38O4 (1289377-52-1) + t-butyldimethylsiyl triflate (69739-34-0) → C34H66O4Si2 (1289377-53-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol2007567

Reference yield:

C15H22O2 (1289377-46-3) → C34H66O4Si2 (1289377-53-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water; tert-butyl alcohol / 20 - 25 °C / Inert atmosphere

2.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - -50 °C / Inert atmosphere

2.2: 3.17 h / -78 °C / Inert atmosphere

3.1: sodium tetrahydroborate; acetic acid / acetonitrile / 4 h / 20 - 25 °C / Inert atmosphere

3.2: 2 h / 20 - 25 °C / Inert atmosphere

4.1: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere

With 2,6-dimethylpyridine; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; acetic acid; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; acetonitrile; tert-butyl alcohol;

DOI:10.1021/ol2007567

Reference yield:

(3S,4R)-1-Benzyloxy-4-methyl-hex-5-en-3-ol (909803-71-0) → C34H66O4Si2 (1289377-53-2)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

1.2: 0 - 25 °C / Inert atmosphere

2.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water; tert-butyl alcohol / 20 - 25 °C / Inert atmosphere

3.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - -50 °C / Inert atmosphere

3.2: 3.17 h / -78 °C / Inert atmosphere

4.1: sodium tetrahydroborate; acetic acid / acetonitrile / 4 h / 20 - 25 °C / Inert atmosphere

4.2: 2 h / 20 - 25 °C / Inert atmosphere

5.1: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere

With 2,6-dimethylpyridine; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; sodium hydride; acetic acid; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; acetonitrile; tert-butyl alcohol;

DOI:10.1021/ol2007567

upstream raw materials:

(3S,4R)-1-Benzyloxy-4-methyl-hex-5-en-3-ol

(4R)-4-benzyl-3-[(2R)-2-methylpentanoyl]-1,3-oxazolidin-2-one

C₁₅H₂₂O₂

C₈H₁₇NO₂