α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile

Base Information

Chemical Name:α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile
CAS No.:103523-56-4
Molecular Formula:C₂₄H₃₂N₂O₂
Molecular Weight:380.53
Hs Code.:

Synonyms:α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile

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Chemical Property of α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile

Chemical Property:

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Technology Process of α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile

There total 4 articles about α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5558-29-2
3-methyl-2-phenyl-butyronitrile

: 103523-56-4
α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaNH₂

2: aq. (COOH)2

3: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium tetrahydroborate; oxalic acid; sodium amide;
DOI:10.1248/cpb.36.373

Reference yield:

: 140-29-4
phenylacetonitrile

: 103523-56-4
α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaNH₂ / 1.) THF, 0.5 h, room temp. 2.) THF, 4 h, room temp.

2: 1.) NaNH₂

3: aq. (COOH)2

4: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium tetrahydroborate; oxalic acid; sodium amide;
DOI:10.1248/cpb.36.373

Reference yield:

: 198996-89-3
5,5-Diethoxy-2-isopropyl-2-phenyl-pentanenitrile

: 103523-56-4
α-isopropyl-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>benzeneacetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: aq. (COOH)2

2: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium tetrahydroborate; oxalic acid;
DOI:10.1248/cpb.36.373