N-propargyl methyl p-methoxyphenyl sulfoximine

Base Information

• Chemical Name: N-propargyl methyl p-methoxyphenyl sulfoximine
• CAS No.: 1402061-10-2
• Molecular Formula: C₁₁H₁₃NO₂S
• Molecular Weight: 223.296
• Mol file: 1402061-10-2.mol

Synonyms:N-propargyl methyl p-methoxyphenyl sulfoximine

Chemical Property of N-propargyl methyl p-methoxyphenyl sulfoximine

Chemical Property:

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Technology Process of N-propargyl methyl p-methoxyphenyl sulfoximine

There total 1 articles about N-propargyl methyl p-methoxyphenyl sulfoximine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

S-(4-methoxyphenyl)-S-methylsulfoximine (77970-95-7) + propargyl bromide (106-96-7) → N-propargyl methyl p-methoxyphenyl sulfoximine (1402061-10-2)

Guidance literature:

S-(4-methoxyphenyl)-S-methylsulfoximine; With potassium hydride; In mineral oil; at 20 ℃; for 0.25h; Inert atmosphere;

propargyl bromide; With tetrabutylammomium bromide; In toluene; mineral oil; at 20 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201200573

Reference yield: 87.0%

2-Iodophenol (533-58-4) + N-propargyl methyl p-methoxyphenyl sulfoximine (1402061-10-2) → C17H17NO3S (1402061-28-2)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N,N,N',N'-tetramethylguanidine; In toluene; at 70 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201200573

upstream raw materials:

S-(4-methoxyphenyl)-S-methylsulfoximine

propargyl bromide

Downstream raw materials:

C₁₇H₁₇NO₃S

Refernces