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8α-hydroxyoxycodone

Base Information
  • Chemical Name:8α-hydroxyoxycodone
  • CAS No.:865844-01-5
  • Molecular Formula:C18H21NO5
  • Molecular Weight:331.368
  • Hs Code.:
8α-hydroxyoxycodone

Synonyms:8α-hydroxyoxycodone

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Chemical Property of 8α-hydroxyoxycodone
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Technology Process of 8α-hydroxyoxycodone

There total 5 articles about 8α-hydroxyoxycodone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
thebaine; With peracetic acid; acetic acid; In water; at -5 - 20 ℃; for 1.5 - 2h;
palladium dihydroxide; In water; at 15 - 20 ℃; for 2h;
With hydrogen; In water; butan-1-ol; at 20 - 25 ℃; for 3h; under 2585.81 Torr; Product distribution / selectivity;
Guidance literature:
With formic acid; 5%-palladium/activated carbon; hydrogen; In methanol; water; at 40 ℃; for 1h; under 3102.97 Torr; Overall yield = 84 %; Overall yield = 6.59 g;
Guidance literature:
With 5%-palladium/activated carbon; hydrogen; In water; at 40 ℃; for 16h; under 3102.97 Torr; Overall yield = 61.8 %; Overall yield = 15.56 g; Sealed tube;
upstream raw materials:

thebaine

thebaine

Downstream raw materials:

oxycodone hydrochloride

Oxycodone

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