4'-nitro-o-benzoylbenzoic acid

Base Information

• Chemical Name: 4'-nitro-o-benzoylbenzoic acid
• CAS No.: 20643-62-3
• Molecular Formula: C₁₄H₉NO₅
• Molecular Weight: 271.229
• Mol file: 20643-62-3.mol

Synonyms:4'-nitro-o-benzoylbenzoic acid

Chemical Property of 4'-nitro-o-benzoylbenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-nitro-o-benzoylbenzoic acid

There total 8 articles about 4'-nitro-o-benzoylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

[2-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-(4-nitro-phenyl)-methanone (190906-39-9) → 4'-nitro-o-benzoylbenzoic acid (20643-62-3)

Guidance literature:

With hydrogenchloride; for 3h;

DOI:10.1021/jf960755i

Reference yield:

(4-nitrophenyl)(o-tolyl)methanone (1218-88-8) → 4'-nitro-o-benzoylbenzoic acid (20643-62-3)

Guidance literature:

With potassium dichromate; sulfuric acid; In acetic acid;

DOI:10.1021/ja00769a027

Reference yield:

2-methylphenyl bromide (95-46-5) → 4'-nitro-o-benzoylbenzoic acid (20643-62-3)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Mg, Et₂O, (ii) /BRN= 386796/, toluene, (iii) CrO₃, aq. H₃PO₄, AcOH

2: K₂Cr₂O₇, H₂SO₄ / aq. acetic acid

With potassium dichromate; sulfuric acid; In acetic acid;

DOI:10.1021/ja00769a027

upstream raw materials:

(4-nitrophenyl)(o-tolyl)methanone

[2-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-(4-nitro-phenyl)-methanone

4,5-dihydro-4,4-dimethyl-2-phenoxazole

4-nitrobenzaldehdye

Downstream raw materials:

4'-nitro-o-benzoylbenzoic acid chloride

2-(4-Nitro-benzoyl)-benzoyl azide

2-(4-nitro-benzoyl)-benzamide

(2-aminophenyl)(4-nitrophenyl)methanone