1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone

Base Information

Chemical Name:1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone
CAS No.:143337-96-6
Molecular Formula:C₂₂H₂₄BrNO₂
Molecular Weight:414.342
Hs Code.:

Synonyms:1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone

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Chemical Property of 1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone

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Technology Process of 1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone

There total 1 articles about 1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 143337-95-5
1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-hydroxylpropanone

: 143337-96-6
1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone

Guidance literature:: With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 20 ℃; Cooling with ice;
DOI:10.1016/j.bmc.2010.01.020

Reference yield:

: 1085743-73-2
C₂₂H₂₅NO₂S

: 143337-96-6
1-[2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl]-(2R)-benzyl-3-bromopropanone

: 1224594-31-3
bis-[N-(2,2-dimethyl-8,8a-dihydro-3aH-indeno[(1S,2R)-1,2]-oxazol-3-yl)-(2R)-benzyl-3-ylpropianamide]sulfide

Guidance literature:: With tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; In water; ethyl acetate; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2010.01.020