m-Xylylenediamine

Base Information

Chemical Name:m-Xylylenediamine
CAS No.:1477-55-0
Deprecated CAS:153326-45-5,554432-83-6,1370444-91-9,2138310-14-0
Molecular Formula:C8H12N2
Molecular Weight:136.197
Hs Code.:29215900
European Community (EC) Number:216-032-5
ICSC Number:1462
NSC Number:61568
UN Number:3267,2735
UNII:1E84B9YLJD
DSSTox Substance ID:DTXSID9029649
Nikkaji Number:J38.174H
Wikipedia:M-Xylylenediamine
Wikidata:Q15726051
ChEMBL ID:CHEMBL384146
Mol file:1477-55-0.mol

Synonyms:1,3-xylenediamine;m-xylenediamine;m-xylylenediamine

Suppliers and Price of m-Xylylenediamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,3-Benzenedimethanamine
250mg
$ 50.00

TCI Chemical
m-Xylylenediamine >99.0%(GC)
25g
$ 23.00

TCI Chemical
m-Xylylenediamine >99.0%(GC)
100g
$ 42.00

TCI Chemical
m-Xylylenediamine >99.0%(GC)
500g
$ 95.00

Sigma-Aldrich
m-Xylylenediamine 99%
500g
$ 98.30

Sigma-Aldrich
m-Xylylenediamine 99%
100g
$ 30.30

Sigma-Aldrich
m-Xylylenediamine 99%
5g
$ 15.50

Arctom
1,3-Benzenedimethanamine
100g
$ 21.00

American Custom Chemicals Corporation
M-XYLYLENEDIAMINE 95.00%
500G
$ 4338.74

American Custom Chemicals Corporation
M-XYLYLENEDIAMINE 95.00%
100G
$ 2457.88

Total 157 raw suppliers

Chemical Property of m-Xylylenediamine

Chemical Property:

Appearance/Colour:clear slightly yellow liquid
Vapor Pressure:15 mm Hg ( 145 °C)
Melting Point:14 °C
Refractive Index:n20/D 1.571(lit.)
Boiling Point:247 °C at 760 mmHg
PKA:9.37±0.10(Predicted)
Flash Point:130.4 °C
PSA：52.04000
Density:1.052 g/cm³
LogP:2.00460
Water Solubility.:Miscible
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:136.100048391
Heavy Atom Count:10
Complexity:83.3
Transport DOT Label:Corrosive

Purity/Quality:

99% ^*data from raw suppliers

1,3-Benzenedimethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): T,C
Hazard Codes:T,C
Statements: 21/22-23-34-43-52/53-20/22
Safety Statements: 26-36/37/39-45-61-28A

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Amines, Aromatic
Canonical SMILES:C1=CC(=CC(=C1)CN)CN
Inhalation Risk:A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C , on spraying or dispersing much faster.
Effects of Short Term Exposure:The substance is corrosive to the eyes, skin and respiratory tract. Inhalation of high concentrations of the fume may cause lung oedema. Corrosive on ingestion.
Effects of Long Term Exposure:Repeated or prolonged contact may cause skin sensitization.
General Description 1,3-Bis(aminomethyl)benzene (meta-xylylenediamine, m-XDA) is a key industrial diamine produced via the hydrogenation of isophthalonitrile (IPN). Catalytic studies reveal that its selectivity is highly dependent on catalyst acidity, with acid sites promoting undesirable condensation side reactions between amines and imines. Supported Ni-Co bimetallic catalysts, particularly when modified with potassium (e.g., 3KNiCo/Al₂O₃), significantly enhance m-XDA selectivity (up to 99.9%) by neutralizing acid sites. High metal loadings (e.g., 20Ni-5Co/Al₂O₃) or the addition of promoters like Fe further improve performance by suppressing both acid sites and hydroxyl group activity, while optimizing reducibility and metal dispersion. These advancements enable efficient m-XDA synthesis even without basic additives.

Technology Process of m-Xylylenediamine

There total 41 articles about m-Xylylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24964-64-5
3-Cyanobenzaldehyde

: 1477-55-0
1,3-di(aminomethyl)benzene

Guidance literature:: With ammonia; hydrogen; In methanol; at 100 ℃; for 5h; under 37503.8 Torr;

Reference yield: 97.0%

: 626-19-7
Isophthalaldehyde

: 1477-55-0
1,3-di(aminomethyl)benzene

Guidance literature:: With Co-doped zirconium dioxide; ammonia; hydrogen; N-butylamine; In methanol; at 99.84 ℃; for 10h; chemoselective reaction; Autoclave;
DOI:10.1039/d0gc02280b

Reference yield: 96.8%

: 626-17-5
benzene-1,3-dicarbonitrile

: 1477-55-0
1,3-di(aminomethyl)benzene

: 100-81-2
3-methyl-benzenemethanamine

Guidance literature:: With hydrogen; Ni(NO₃)2, Cu(NO₃)2, Cr(NO₃)3, Na₂CO₃; calcined at 380 deg C for 18 h; pretreatment is given in full text; In 1,2,4-Trimethylbenzene; ammonia; at 80 ℃; for 24h; Product distribution / selectivity;