C₈H₅BrFN₃

Base Information

• Chemical Name: C₈H₅BrFN₃
• CAS No.: 1198612-89-3
• Molecular Formula: C₈H₅BrFN₃
• Molecular Weight: 242.05
• Mol file: 1198612-89-3.mol

Synonyms:C₈H₅BrFN₃

Chemical Property of C₈H₅BrFN₃

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₈H₅BrFN₃

There total 1 articles about C₈H₅BrFN₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-(3-fluorophenyl)-2H-1,2,3-triazole (1198612-83-7,1235527-61-3) → C8H5BrFN3 (1198612-89-3)

Guidance literature:

With N-Bromosuccinimide; In Isopropyl acetate; at 20 ℃;

DOI:10.1021/ol902334x

Reference yield: 90.0%

bromoacetic acid tert-butyl ester (5292-43-3) + C8H5BrFN3 (1198612-89-3) → C14H15BrFN3O2 (1198613-36-3) + C14H15BrFN3O2 (1198613-34-1) + C14H15BrFN3O2 (1198613-38-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at -10 - 0 ℃; regioselective reaction;

DOI:10.1021/ol902334x

Reference yield: 89.0%

ethyl bromide (74-96-4) + C8H5BrFN3 (1198612-89-3) → C10H9BrFN3 (1198613-24-9) + C10H9BrFN3 (1198613-28-3) + C10H9BrFN3 (1198613-26-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; regioselective reaction;

DOI:10.1021/ol902334x

upstream raw materials:

4-(3-fluorophenyl)-2H-1,2,3-triazole

Downstream raw materials:

C₁₀H₉BrFN₃

C₁₀H₉BrFN₃

C₁₀H₉BrFN₃

C₁₄H₁₅BrFN₃O₂