Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester

Base Information

• Chemical Name: Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester
• CAS No.: 75930-84-6
• Molecular Formula: C₁₃H₂₀O₃
• Molecular Weight: 224.3
• Mol file: 75930-84-6.mol

Synonyms:Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester

Chemical Property of Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester

There total 4 articles about Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-(3-Hydroxy-butyl)-3-methyl-cyclohex-2-enone (75930-83-5) + acetyl chloride (75-36-5) → Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester (75930-84-6)

Guidance literature:

In pyridine; dichloromethane;

DOI:10.1021/ja00545a017

Reference yield:

2-methyl-2,3,4,6,7,8-hexahydro-chromen-5-one (34084-82-7) → Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester (75930-84-6)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether / 1.) -40 deg C, 25 min, 2.) 0 deg C, 5 min, 3.) room temperature, 1 h

2: 100 percent / aq. HCl / diethyl ether / 0.17 h

3: 87 percent / pyridine; CH₂Cl₂

With hydrogenchloride; In pyridine; diethyl ether; dichloromethane;

DOI:10.1021/ja00545a017

Reference yield:

1,3-cylohexanedione (504-02-9) → Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohex-1-enyl)-propyl ester (75930-84-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 2.) sodium borohydride / 1.) water, room temperature, 25 h, 2.) ethanol, -15 deg C, 2 h; room temperature, 3 h

2: diethyl ether / 1.) -40 deg C, 25 min, 2.) 0 deg C, 5 min, 3.) room temperature, 1 h

3: 100 percent / aq. HCl / diethyl ether / 0.17 h

4: 87 percent / pyridine; CH₂Cl₂

With hydrogenchloride; sodium tetrahydroborate; In pyridine; diethyl ether; dichloromethane;

DOI:10.1021/ja00545a017

upstream raw materials:

2-(3-Hydroxy-butyl)-3-methyl-cyclohex-2-enone

acetyl chloride

2-methyl-2,3,4,6,7,8-hexahydro-chromen-5-one

1,3-cylohexanedione

Downstream raw materials:

Acetic acid 1-methyl-3-(2-methyl-6-oxo-cyclohexyl)-propyl ester