2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt

Base Information

• Chemical Name: 2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt
• CAS No.: 97879-00-0
• Molecular Formula: C₁₃H₁₄N₂OS*ClH
• Molecular Weight: 282.794
• Mol file: 97879-00-0.mol

Synonyms:2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt

Chemical Property of 2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt

There total 5 articles about 2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-(benzylthio)salicylamide (54705-18-9) → 2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt (97879-00-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / borane / tetrahydrofuran / 15 h / Heating

2: 57 percent / 1) room temp., 24 h; 2) reflux, 24 h

3: 63 percent / borane / tetrahydrofuran / 24 h / Heating

With borane; In tetrahydrofuran;

DOI:10.1021/ja00307a043

Reference yield:

2-(benzylthio)benzylamine (97878-93-8) → 2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt (97879-00-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 57 percent / 1) room temp., 24 h; 2) reflux, 24 h

2: 63 percent / borane / tetrahydrofuran / 24 h / Heating

With borane; In tetrahydrofuran;

DOI:10.1021/ja00307a043

Reference yield:

2-<2-(benzylthio)phenyl>-4-carbethoxy-5-methylimidazole (97878-94-9) → 2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt (97879-00-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 63 percent / borane / tetrahydrofuran / 24 h / Heating

With borane; In tetrahydrofuran;

DOI:10.1021/ja00307a043

upstream raw materials:

acetic anhydride

2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride

S-(benzylthio)salicylamide

2-<2-(benzylthio)phenyl>-4,5-dimethylimidazole

Refernces