2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride

Base Information

• Chemical Name: 2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride
• CAS No.: 97878-99-4
• Molecular Formula: C₁₁H₁₂N₂S*ClH
• Molecular Weight: 240.757
• Mol file: 97878-99-4.mol

Synonyms:2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride

Chemical Property of 2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride

There total 4 articles about 2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-(benzylthio)salicylamide (54705-18-9) → 2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride (97878-99-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / borane / tetrahydrofuran / 15 h / Heating

2: 57 percent / 1) room temp., 24 h; 2) reflux, 24 h

3: 63 percent / borane / tetrahydrofuran / 24 h / Heating

With borane; In tetrahydrofuran;

DOI:10.1021/ja00307a043

Reference yield:

2-(benzylthio)benzylamine (97878-93-8) → 2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride (97878-99-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 57 percent / 1) room temp., 24 h; 2) reflux, 24 h

2: 63 percent / borane / tetrahydrofuran / 24 h / Heating

With borane; In tetrahydrofuran;

DOI:10.1021/ja00307a043

Reference yield:

2-<2-(benzylthio)phenyl>-4-carbethoxy-5-methylimidazole (97878-94-9) → 2-(2-mercaptophenyl)-4,5-dimethylimidazole hydrochloride (97878-99-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / borane / tetrahydrofuran / 24 h / Heating

With borane; In tetrahydrofuran;

DOI:10.1021/ja00307a043

upstream raw materials:

2-<2-(benzylthio)phenyl>-4,5-dimethylimidazole

S-(benzylthio)salicylamide

2-(benzylthio)benzylamine

2-<2-(benzylthio)phenyl>-4-carbethoxy-5-methylimidazole

Downstream raw materials:

2,4-Dinitrophenol

Thioacetic acid S-[2-(4,5-dimethyl-1H-imidazol-2-yl)-phenyl] ester

4-nitro-phenol

2-<2-(acetylthio)phenyl>-4,5-dimethylimidazole HCl salt

Refernces