(3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone

Base Information

Chemical Name:(3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone
CAS No.:1416163-99-9
Molecular Formula:C₂₆H₁₉Cl₂F₂N₃O₄
Molecular Weight:546.357
Hs Code.:

Synonyms:(3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone

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Chemical Property of (3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone

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Technology Process of (3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone

There total 4 articles about (3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86386-76-7,123632-22-4,141113-42-0,150024-48-9
1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole

: 1416163-99-9
(3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; tetrabutylammomium bromide / ethyl acetate / 12 h / Reflux; Inert atmosphere

2: potassium carbonate; dihydrogen peroxide / water; methanol / 3 h / 20 °C

With tetrabutylammomium bromide; dihydrogen peroxide; potassium carbonate; In methanol; water; ethyl acetate;

Reference yield:

: 99-93-4
4-Hydroxyacetophenone

: 1416163-99-9
(3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate; tetrabutylammomium bromide / ethyl acetate / 12 h / Inert atmosphere; Reflux

2: sodium hydroxide / water; methanol / 18 h / 20 °C

3: potassium carbonate; dihydrogen peroxide / water; methanol / 3 h / 20 °C

With tetrabutylammomium bromide; dihydrogen peroxide; potassium carbonate; sodium hydroxide; In methanol; water; ethyl acetate;

Reference yield:

: 1416163-70-6
1-(4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)ethanone

: 1416163-99-9
(3-(2,4-dichlorophenyl)oxiran-2-yl) (4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water; methanol / 18 h / 20 °C

2: potassium carbonate; dihydrogen peroxide / water; methanol / 3 h / 20 °C

With dihydrogen peroxide; potassium carbonate; sodium hydroxide; In methanol; water;