<2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane

Base Information

• Chemical Name: <2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane
• CAS No.: 153595-01-8
• Molecular Formula: C₁₅H₂₆O₅
• Molecular Weight: 286.368
• Mol file: 153595-01-8.mol

Synonyms:<2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane

Chemical Property of <2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane

There total 3 articles about <2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(2R,2'S,2''R,2'''R,2''''S,3S,4S,6'S,6''S,6'''S,6''''S)-3-O-benzyl-1-O,2-O:4-O,5-O-di-(6,6'-dimethyl-3,3',4,4',5,5',6,6'-octahydro-2,2'-diyl)-adonitol → <2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane (153595-01-8) + (2R,2'S,2''R,3S,4S,6'S,6''S)-3-O-benzyl-1-O,2-O-(6,6'-dimethyl-3,3',4,4',5,5',6,6'-octahydro-2,2'-diyl)-adonitol (173397-77-8)

Guidance literature:

With camphor-10-sulfonic acid; glycerol; In chloroform; for 42h; Heating;

DOI:10.1016/0957-4166(95)00318-J

Reference yield: 83.0%

(2S,6S,7R,9S,14S)-14-Benzyloxymethyl-2,9-dimethyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane (153595-03-0) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → (R)-3-benzyloxy-1,2-propanediol (56552-80-8) + <2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane (153595-01-8)

Guidance literature:

camphor-10-sulfonic acid; In toluene; for 2h; Heating;

DOI:10.1016/S0040-4039(00)73906-2

Reference yield: 75.0%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) + (2R,2'S,2''R,2'''R,2''''S,3S,4S,6'S,6''S,6'''S,6''''S)-3-O-benzyl-1-O,2-O:4-O,5-O-di-(6,6'-dimethyl-3,3',4,4',5,5',6,6'-octahydro-2,2'-diyl)-adonitol → <2S, 6S, 7R, 9S, 14S>-2,9-dimethyl-14-hydroxymethyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane (153595-01-8) + (2R,2'S,2''R,3S,4S,6'S,6''S)-3-O-benzyl-1-O,2-O-(6,6'-dimethyl-3,3',4,4',5,5',6,6'-octahydro-2,2'-diyl)-adonitol (173397-77-8)

Guidance literature:

With camphor-10-sulfonic acid; In chloroform; for 42h; Heating;

DOI:10.1016/0957-4166(95)00318-J

upstream raw materials:

(2S,6S,7R,9S,14S)-14-Benzyloxymethyl-2,9-dimethyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane

glycerol

Downstream raw materials:

(2S,6S,7R,9S,14S)-14-Benzyloxymethyl-2,9-dimethyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane