Methyl 2-[(4-chlorobenzoyl)amino]acetate

Base Information

Chemical Name:Methyl 2-[(4-chlorobenzoyl)amino]acetate
CAS No.:59893-99-1
Molecular Formula:C₁₀H₁₀ClNO₃
Molecular Weight:227.647
Hs Code.:
DSSTox Substance ID:DTXSID801261560
Nikkaji Number:J3.082.575F

Synonyms:Glycine, N-(4-chlorobenzoyl)-, methyl ester;59893-99-1;methyl 2-[(4-chlorobenzoyl)amino]acetate;TimTec1_003162;SCHEMBL4223717;DTXSID801261560;HMS1542P16;STK026251;AKOS001117240;N-(4-Chlorobenzoyl)glycine methyl ester;methyl N-[(4-chlorophenyl)carbonyl]glycinate;SR-01000213600;SR-01000213600-1;BRD-K88454167-001-01-6;Z20189685

Suppliers and Price of Methyl 2-[(4-chlorobenzoyl)amino]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 2-[(4-chlorobenzoyl)amino]acetate

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:227.0349209
Heavy Atom Count:15
Complexity:237

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)CNC(=O)C1=CC=C(C=C1)Cl

Technology Process of Methyl 2-[(4-chlorobenzoyl)amino]acetate

There total 8 articles about Methyl 2-[(4-chlorobenzoyl)amino]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 5680-79-5,883886-67-7
glycine ethyl ester hydrochloride

: 122-01-0
4-chloro-benzoyl chloride

: 59893-99-1
N-(p-chlorobenzoyl)-glycine methyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 25 ℃; for 4h; Reagent/catalyst; Solvent;

Reference yield: 79.0%

: 5680-79-5,883886-67-7
glycine ethyl ester hydrochloride

: 873-76-7
para-Chlorobenzyl alcohol

: 59893-99-1
N-(p-chlorobenzoyl)-glycine methyl ester

Guidance literature:: With tert.-butylhydroperoxide; iron(II) chloride tetrahydrate; calcium carbonate; In water; acetonitrile; at 80 ℃; for 4h; Sealed tube;
DOI:10.1016/j.tet.2014.06.001

Reference yield: 77.0%

: 5680-79-5,883886-67-7
glycine ethyl ester hydrochloride

: 104-88-1
4-chlorobenzaldehyde

: 59893-99-1
N-(p-chlorobenzoyl)-glycine methyl ester

Guidance literature:: With tert.-butylhydroperoxide; copper(ll) sulfate pentahydrate; calcium carbonate; In water; acetonitrile; at 20 ℃; Inert atmosphere;
DOI:10.1021/jo301252c DOI:10.1021/jo301252c