4-Iodo-N-[4-[1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]benzamide

Base Information

Chemical Name:4-Iodo-N-[4-[1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]benzamide
CAS No.:211313-57-4
Molecular Formula:C₁₉H₂₃IN₂O₃S
Molecular Weight:486.374
Hs Code.:
DSSTox Substance ID:DTXSID801137735

Synonyms:DTXSID801137735;4-Iodo-N-[4-[1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]benzamide;211313-57-4

Suppliers and Price of 4-Iodo-N-[4-[1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Iodo-N-[4-[1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]benzamide

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:486.04741
Heavy Atom Count:26
Complexity:546

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)S(=O)(=O)NCC(C)C1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)I

Technology Process of 4-Iodo-N-[4-[1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]benzamide

There total 3 articles about 4-Iodo-N-[4-[1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1711-02-0
4-iodobenzoic acid chloride

: 211315-28-5
N-[2-(4-aminophenyl)propyl]propane-2-sulfonamide

: 211313-57-4
N-2-(4-N-(benzamido)phenyl)propyl 2-propanesulfonamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1021/jm000462n

Reference yield:

: 211315-27-4
N-2-(4-(N',N'-dibenzylamino)phenyl)propyl 2-propanesulfonamide

: 211313-57-4
N-2-(4-N-(benzamido)phenyl)propyl 2-propanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / ammonium formate; H₂ / 10percent Pd/C / ethanol / 6 h / 25 °C

2: 73 percent / triethylamine / CH₂Cl₂ / 20 °C

With hydrogen; ammonium formate; triethylamine; 10percent Pd/C; In ethanol; dichloromethane;
DOI:10.1021/jm000462n

Reference yield:

: 2-(4-(N,N-dibenzylamino)phenyl)propylamine hydrochloride

: 211313-57-4
N-2-(4-N-(benzamido)phenyl)propyl 2-propanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 63 percent / triethylamine / CH₂Cl₂ / 7 h / 0 - 20 °C

2: 93 percent / ammonium formate; H₂ / 10percent Pd/C / ethanol / 6 h / 25 °C

3: 73 percent / triethylamine / CH₂Cl₂ / 20 °C

With hydrogen; ammonium formate; triethylamine; 10percent Pd/C; In ethanol; dichloromethane;
DOI:10.1021/jm000462n