Technology Process of (Z)-1,2,3,4,5-pentafluoro-6-(4-phenylbut-1-en-1-yl)benzene
There total 3 articles about (Z)-1,2,3,4,5-pentafluoro-6-(4-phenylbut-1-en-1-yl)benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); silver carbonate;
In
dimethyl sulfoxide;
at 70 ℃;
for 10h;
stereoselective reaction;
Inert atmosphere;
DOI:10.1246/cl.2011.978
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / diethyl ether; hexane / -78 - 20 °C
1.2: -78 - 20 °C
2.1: dimethylsulfide borane complex; cyclohexene / diethyl ether / 1.5 h / 0 - 20 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: tetrakis(triphenylphosphine) palladium(0); silver carbonate / dimethyl sulfoxide / 10 h / 70 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; dimethylsulfide borane complex; silver carbonate; cyclohexene;
In
diethyl ether; hexane; dimethyl sulfoxide;
DOI:10.1246/cl.2011.978
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dimethylsulfide borane complex; cyclohexene / diethyl ether / 1.5 h / 0 - 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: tetrakis(triphenylphosphine) palladium(0); silver carbonate / dimethyl sulfoxide / 10 h / 70 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); dimethylsulfide borane complex; silver carbonate; cyclohexene;
In
diethyl ether; dimethyl sulfoxide;
DOI:10.1246/cl.2011.978
