6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone

Base Information

• Chemical Name: 6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone
• CAS No.: 82801-28-3
• Molecular Formula: C₂₁H₂₅NO₆
• Molecular Weight: 387.433
• Mol file: 82801-28-3.mol

Synonyms:6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone

Chemical Property of 6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone

There total 1 articles about 6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

6,7-Dimethoxy-2-methyl-1-(3,4,5-trimethoxy-phenyl)-2H-isoquinolin-3-one (82791-57-9) → 6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone (82801-28-3)

Guidance literature:

With sodium tetrahydroborate; In butan-1-ol; at 100 ℃; for 2h;

DOI:10.1055/s-1982-29848

Reference yield: 70.0%

6,7-dimethoxy-2-methyl-3-oxo-1-(3,4,5-trimethoxy)-1,2,3,4-tetrahydroisoquinolone (82801-28-3) → 6,7-dimethoxy-1-(3,4,5-trimethoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline (22324-83-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 3h; Heating;

DOI:10.1055/s-1982-29848

upstream raw materials:

6,7-Dimethoxy-2-methyl-1-(3,4,5-trimethoxy-phenyl)-2H-isoquinolin-3-one

Downstream raw materials:

6,7-dimethoxy-1-(3,4,5-trimethoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline