4-(Chloromethyl)-3-nitrobenzoic acid

Base Information

Chemical Name:4-(Chloromethyl)-3-nitrobenzoic acid
CAS No.:103440-03-5
Molecular Formula:C₈H₆ClNO₄
Molecular Weight:215.593
Hs Code.:
European Community (EC) Number:968-240-7

Synonyms:4-(chloromethyl)-3-nitrobenzoic acid;103440-03-5;SCHEMBL2292095;OOCUPQDMNUETMI-UHFFFAOYSA-N;3-nitro-p-chloromethylbenzoic acid;4-(chloromethyl)-3-nitrobenzoicacid;MFCD26801843;EN300-267527;G48860

Suppliers and Price of 4-(Chloromethyl)-3-nitrobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-(Chloromethyl)-3-nitrobenzoic acid

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:214.9985354
Heavy Atom Count:14
Complexity:240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(=O)O)[N+](=O)[O-])CCl

Technology Process of 4-(Chloromethyl)-3-nitrobenzoic acid

There total 4 articles about 4-(Chloromethyl)-3-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1642-81-5
p-(chloromethyl)benzoic acid

: 103440-03-5
3-nitro-(4-chloromethyl) benzoic acid

Guidance literature:: With sulfuric acid; nitric acid; at 0 ℃; for 1.5h;
DOI:10.1016/j.poly.2020.114752

Reference yield:

: 7499-07-2
4-chloro-2-methylbenzoic acid

: 103440-03-5
3-nitro-(4-chloromethyl) benzoic acid

Guidance literature:: With nitric acid; at 15 ℃;

Reference yield:

: 99-94-5
p-Toluic acid

: 103440-03-5
3-nitro-(4-chloromethyl) benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuryl chloride, benzoyl peroxide / 2 h / Heating; Irradiation

2: HNO₃, H₂SO₄ / below -10 deg C

With sulfuryl dichloride; Perbenzoic acid; sulfuric acid; nitric acid;
DOI:10.1002/(SICI)1097-4601(1996)28:4<283::AID-KIN6>3.0.CO;2-R