1642-81-5Relevant articles and documents
-
Zamorsky
, p. 1980 (1958)
-
Preparation method of 4-formylbenzoic acid
-
, (2020/11/23)
The invention provides a preparation method of 4-formylbenzoic acid, and the method comprises the following steps: by using 4-methylbenzoyl chloride as a raw material, performing chlorinating to obtain 4-chloromethylbenzoyl chloride, performing hydrolyzing to obtain 4-chloromethyl benzoic acid, and reacting with urotropine to obtain 4-formylbenzoic acid. The method provided by the invention is simple in process, does not need special equipment and is relatively low in cost; moreover, the method provided by the invention is relatively high in product yield and purity, and large-scale industrialproduction is easy to realize. The result of the embodiment shows that the yield of each step of the preparation method of the 4-formylbenzoic acid provided by the invention is greater than or equalto 90%, and the purity of the finally obtained 4-formylbenzoic acid is greater than or equal to 99.7%.
Highly selective halogenation of unactivated C(sp3)-H with NaX under co-catalysis of visible light and Ag@AgX
Liu, Shouxin,Zhang, Qi,Tian, Xia,Fan, Shiming,Huang, Jing,Whiting, Andrew
, p. 4729 - 4737 (2018/10/23)
The direct selective halogenation of unactivated C(sp3)-H bonds into C-halogen bonds was achieved using a nano Ag/AgCl catalyst at RT under visible light or LED irradiation in the presence of an aqueous solution of NaX/HX as a halide source, in air. The halogenation of hydrocarbons provided mono-halide substituted products with 95% selectivity and yields higher than 90%, with the chlorination of toluene being 81%, far higher than the 40% conversion using dichlorine. Mechanistic studies demonstrated that the reaction is a free radical process using blue light (450-500 nm), with visible light being the most effective light source. Irradiation is proposed to cause AgCl bonding electrons to become excited and electron transfer from chloride ions induces chlorine radical formation which drives the substitution reaction. The reaction provides a potentially valuable method for the direct chlorination of saturated hydrocarbons.