(S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride

Base Information

• Chemical Name: (S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride
• CAS No.: 126090-42-4
• Molecular Formula: C₁₆H₁₈N₂O*ClH
• Molecular Weight: 290.793
• Mol file: 126090-42-4.mol

Synonyms:(S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride

Chemical Property of (S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride

There total 7 articles about (S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(S)-N-Boc-phenylalanine benzylamide (33662-25-8,114530-49-3,84235-32-5) → (S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride (126090-42-4,34582-43-9)

Guidance literature:

With hydrogenchloride; In dichloromethane; ethyl acetate; at 0 - 20 ℃; for 3h;

Reference yield: 94.0%

N-[N-[(2S,3S)-N-Methyl-3-ethoxycarbonylaziridine-2-carbonyl]-L-phenylalanyl]isopentylamine (173898-70-9) + benzyl bromide (100-39-0) → N-[N-[(2S,3S)-N-benzyl-3-ethoxycarbonylaziridine-2-carbonyl]-L-phenylalanyl]benzylamine (173899-21-3) + (S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride (126090-42-4,34582-43-9)

Guidance literature:

With sodium hydroxide; sodium chloride; sodium carbonate; In ethanol; hexane; water; ethyl acetate; N,N-dimethyl-formamide;

Reference yield: 60.0%

→ (S)-2-amino-N-benzyl-3-phenylpropionamide hydrochloride (126090-42-4,34582-43-9)

Guidance literature:

upstream raw materials:

(S)-N-Boc-phenylalanine benzylamide

N-tert-butoxycarbonyl-L-phenylalanine

Boc-Phe-O-COO-isoBu

benzylamine

Downstream raw materials:

Boc-Gln-D-Trp(CHO)-Phe-NHBzl

(R)-2-Amino-N-((S)-1-benzylcarbamoyl-2-phenyl-ethyl)-3-(1-formyl-1H-indol-3-yl)-propionamide; hydrochloride

Boc-D-Trp(CHO)-Phe-NHBzl

[(S)-1-Benzyl-4-((S)-1-benzylcarbamoyl-2-phenyl-ethylamino)-2-hydroxy-butyl]-carbamic acid tert-butyl ester