C₁₀H₉F₃O

Base Information

• Chemical Name: C₁₀H₉F₃O
• CAS No.: 1380233-12-4
• Molecular Formula: C₁₀H₉F₃O
• Molecular Weight: 202.176
• Mol file: 1380233-12-4.mol

Synonyms:C₁₀H₉F₃O

Chemical Property of C₁₀H₉F₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₉F₃O

There total 4 articles about C₁₀H₉F₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(4,4,4-trifluorobut-1-en-2-yl)benzene (104798-41-6) → C10H9F3O (1380233-12-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; at 0 ℃; for 3h; pH=7; aq. phosphate buffer;

DOI:10.1002/anie.201201095

Reference yield:

1-phenyl vinyl triflate (28143-79-5) → C10H9F3O (1380233-12-4)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride / tetrahydrofuran; diethyl ether

2: copper(l) iodide / methanol / 24 h / 20 °C / Inert atmosphere

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane; water / 3 h / 0 °C / pH 7 / aq. phosphate buffer

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; 3-chloro-benzenecarboperoxoic acid; lithium chloride; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water;

DOI:10.1002/anie.201201095

Reference yield:

2-phenylallyltrimethylsilane (77130-15-5) → C10H9F3O (1380233-12-4)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) iodide / methanol / 24 h / 20 °C / Inert atmosphere

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane; water / 3 h / 0 °C / pH 7 / aq. phosphate buffer

With copper(l) iodide; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; water;

DOI:10.1002/anie.201201095

upstream raw materials:

(4,4,4-trifluorobut-1-en-2-yl)benzene

1-phenyl vinyl triflate

2-phenylallyltrimethylsilane

acetophenone

Downstream raw materials:

[3-(trifluoromethyl)hept-1-en-2-yl]benzene

(Z)-trifluoromethylated 2-phenyl allylic alcohol

(E)-2-phenyl-4,4,4-trifluorobut-2-en-1-ol

5-(4,4,4-trifluorobut-1-en-2-yl)benzo[d][1,3]dioxole