Technology Process of methacrylamido(phenyl)methylphosphonic acid
There total 3 articles about methacrylamido(phenyl)methylphosphonic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
water;
at 14 - 21 ℃;
for 2.33333h;
- Guidance literature:
-
diethyl [(methacrylamido)(phenyl)methyl]phosphonate;
With
trimethylsilyl bromide;
In
dichloromethane;
at 40 ℃;
for 2h;
Cooling with ice;
Inert atmosphere;
With
methanol;
at 20 ℃;
for 12h;
DOI:10.1002/pola.27025
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ammonium carbonate; aluminium(III) triflate / neat (no solvent) / 100 °C
2.1: triethylamine / toluene / 2 h / 20 °C / Inert atmosphere; Cooling with ice
3.1: trimethylsilyl bromide / dichloromethane / 2 h / 40 °C / Cooling with ice; Inert atmosphere
3.2: 12 h / 20 °C
With
aluminium(III) triflate; trimethylsilyl bromide; ammonium carbonate; triethylamine;
In
dichloromethane; toluene;
DOI:10.1002/pola.27025
