2-Amino-4-(2-nitrophenyl)butyric acid

Base Information

Chemical Name:2-Amino-4-(2-nitrophenyl)butyric acid
CAS No.:105260-07-9
Molecular Formula:C₁₀H₁₂N₂O₄
Molecular Weight:224.216
Hs Code.:
DSSTox Substance ID:DTXSID901292740

Synonyms:2-amino-4-(2-nitrophenyl)butyric acid;105260-07-9;SCHEMBL10416252;ANELVGMNCPNANJ-UHFFFAOYSA-N;DTXSID901292740;AKOS012362780;alpha-Amino-2-nitrobenzenebutanoic acid;2-amino-4-(2-nitrophenyl)-butyric acid

Suppliers and Price of 2-Amino-4-(2-nitrophenyl)butyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Amino-4-(2-nitrophenyl)butyric acid

Chemical Property:

XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:224.07970687
Heavy Atom Count:16
Complexity:264

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CCC(C(=O)O)N)[N+](=O)[O-]

Technology Process of 2-Amino-4-(2-nitrophenyl)butyric acid

There total 2 articles about 2-Amino-4-(2-nitrophenyl)butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16793-89-8
(2-bromoethyl)-2-nitrobenzene

: 105260-07-9
2-amino-4-(2-nitrophenyl)butyric acid

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / NaH / dimethylformamide / 20 h / Ambient temperature

2: HCl, AcOH / 9 h / Heating

With hydrogenchloride; sodium hydride; acetic acid; In N,N-dimethyl-formamide;
DOI:10.1021/ja953578v

Reference yield:

: 86499-31-2
ethyl 2-(acetylamino)-2-(ethoxycarbonyl)-4-(2-nitrophenyl)butanoate

: 105260-07-9
2-amino-4-(2-nitrophenyl)butyric acid

Guidance literature:: With hydrogenchloride; acetic acid; for 9h; Heating;
DOI:10.1021/ja953578v

Reference yield:

: 105260-07-9
2-amino-4-(2-nitrophenyl)butyric acid

: 2-[2-(3-tert-Butoxycarbonylamino-4-hydroxy-butyl)-phenylamino]-3-methyl-butyric acid

Guidance literature:: Multi-step reaction with 6 steps

1: SOCl₂ / 6 h / Ambient temperature

2: CH₂Cl₂ / 36 h / Ambient temperature

3: 63 percent / LiBH₄ / tetrahydrofuran / 1.) 0 deg C, 1 h, 2.) RT, 48 h

4: 98 percent / H₂ / 10percent Pd/C / ethanol / 3 h / 760 Torr / Ambient temperature

5: 2.) NaBH₃CN, 3.) H₂ / 3.) Pd/C

6: 2 N aq. KOH / methanol / 24 h / Ambient temperature

With potassium hydroxide; lithium borohydride; thionyl chloride; hydrogen; sodium cyanoborohydride; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1021/ja953578v