3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester

Base Information

• Chemical Name: 3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester
• CAS No.: 107199-57-5
• Molecular Formula: C₂₅H₃₄N₂O₃
• Molecular Weight: 410.557
• Mol file: 107199-57-5.mol

Synonyms:3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester

Chemical Property of 3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester

There total 2 articles about 3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(E)-3-Phenyl-acrylic acid 4-{(2-cyano-ethyl)-[(E)-(3-phenyl-acryloyl)]-amino}-butyl ester (107199-58-6) → 3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester (107199-57-5)

Guidance literature:

With hydrogen; platinum(IV) oxide;

DOI:10.1016/S0040-4039(00)83978-7

Reference yield:

3-<(4-Hydroxybutyl)amino>propannitril (107199-54-2) → 3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester (107199-57-5)

Guidance literature:

Multi-step reaction with 2 steps

2: 90 percent / H₂ / platinum oxide

With hydrogen; platinum(IV) oxide;

DOI:10.1016/S0040-4039(00)83978-7

Reference yield: 80.0%

3-Phenyl-propionic acid 4-[(3-amino-propyl)-(3-phenyl-propionyl)-amino]-butyl ester (107199-57-5) + (S)-3-(tert-butoxycarbonylamino)-3-phenylpropanoic acid (103365-47-5) → 3-Phenyl-propionic acid 4-[[3-((S)-3-tert-butoxycarbonylamino-3-phenyl-propionylamino)-propyl]-(3-phenyl-propionyl)-amino]-butyl ester (107199-59-7)

Guidance literature:

With 2-chloro-1-methyl-pyridinium iodide;

DOI:10.1016/S0040-4039(00)83978-7

upstream raw materials:

(E)-3-Phenyl-acrylic acid 4-{(2-cyano-ethyl)-[(E)-(3-phenyl-acryloyl)]-amino}-butyl ester

3-<(4-Hydroxybutyl)amino>propannitril

Downstream raw materials:

3-Phenyl-propionic acid 4-[[3-((S)-3-tert-butoxycarbonylamino-3-phenyl-propionylamino)-propyl]-(3-phenyl-propionyl)-amino]-butyl ester

(-)-dihydrocelacinnine

((S)-2-{3-[(4-Oxo-butyl)-(3-phenyl-propionyl)-amino]-propylcarbamoyl}-1-phenyl-ethyl)-carbamic acid tert-butyl ester

((S)-2-{3-[(4-Hydroxy-butyl)-(3-phenyl-propionyl)-amino]-propylcarbamoyl}-1-phenyl-ethyl)-carbamic acid tert-butyl ester