(1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate

Base Information

Chemical Name:(1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate
CAS No.:1338323-15-1
Molecular Formula:C₂₈H₃₀F₃NO₄S
Molecular Weight:533.612
Hs Code.:

Synonyms:(1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate

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Technology Process of (1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate

There total 1 articles about (1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2516-99-6
3,3,3-Trifluoropropionic acid

: 187324-63-6
(1R,2S)-2-[N-benzyl-N-(mesitylenesulfonyl)amino]-1-phenyl-1-propanol

: 1338323-15-1
(1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.08.034

Reference yield:

: 1338323-15-1
(1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl 3,3,3-trifluoropropanoate

: 100-52-7
benzaldehyde

: C₃₅H₃₆F₃NO₅S

: 1338323-25-3
C₃₅H₃₆F₃NO₅S

: C₃₅H₃₆F₃NO₅S

Guidance literature:: With bis-exo-2-norbornylboron triflate; triethylamine; In dichloromethane; at -78 ℃; for 8h; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.08.034