2-(phenylselanyl)benzonitrile

Base Information

• Chemical Name: 2-(phenylselanyl)benzonitrile
• CAS No.: 107037-20-7
• Molecular Formula: C₁₃H₉NSe
• Molecular Weight: 258.181
• Mol file: 107037-20-7.mol

Synonyms:2-(phenylselanyl)benzonitrile

Chemical Property of 2-(phenylselanyl)benzonitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(phenylselanyl)benzonitrile

There total 14 articles about 2-(phenylselanyl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

diphenyl diselenide (1666-13-3) + anthranilic acid nitrile (1885-29-6) → 2-(phenylselanyl)benzonitrile (107037-20-7)

Guidance literature:

With tert.-butylnitrite; 5,10,15,20-tetraphenylporphinatonickel(II); In dimethyl sulfoxide; at 0 - 20 ℃; for 6h; Reagent/catalyst; Solvent; Inert atmosphere; Irradiation;

DOI:10.1002/adsc.201801737

Reference yield: 89.4%

2-Chlorobenzonitrile (873-32-5) + diphenyl diselenide (1666-13-3) → 2-(phenylselanyl)benzonitrile (107037-20-7)

Guidance literature:

diphenyl diselenide; With sodium methylate; hydrazine hydrate; In methanol; dimethyl sulfoxide; for 0.0833333h; Inert atmosphere;

2-Chlorobenzonitrile; In methanol; dimethyl sulfoxide; at 130 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c3cc39269d

Reference yield: 87.0%

diphenyl diselenide (1666-13-3) + 2-Cyanophenylboronic acid (138642-62-3) → 2-(phenylselanyl)benzonitrile (107037-20-7)

Guidance literature:

With copper(II) ferrite; In dimethyl sulfoxide; at 100 ℃; for 12h; Green chemistry;

DOI:10.1039/c2ra22415a

upstream raw materials:

2-Chlorobenzonitrile

diphenyl diselenide

o-cyanobromobenzene

sodium phenylselenide

Downstream raw materials:

2-(phenylselanyl)benzoic acid

2-(phenylselanyl)benzoyl chloride

(2-(phenylselanyl)phenyl)methanamine

2,2'-dicyanodiphenyl diselenide

Refernces

• 1、 Fukuzawa, Shin-Ichi,Tanihara, Daisuke,Kikuchi, Satoshi. "Palladium-catalyzed coupling reaction of diaryl dichalcogenide with aryl bromide leading to the synthesis of unsymmetrical aryl chalcogenide". . p. 2145 - 2147. Retrieved 2006.
• 2、 Bürger, Marcel,Ball, Liam T.,Barber, Thomas,Ehrhardt, Nadine,Jones, Peter G.,Namyslo, Jan C.,Werz, Daniel B.. "Phosphine-Catalyzed Aryne Oligomerization: Direct Access to α,ω-Bisfunctionalized Oligo(ortho-arylenes)". supporting information. p. 16796 - 16803. Retrieved 2021/10/20.
• 3、 Zhou, Yao,Wang, Ya,Lou, Yixian,Song, Qiuling. "Facile synthesis of 1,2-thiobenzonitriles: Via Cu-catalyzed denitrogenative radical coupling reaction". supporting information. p. 10265 - 10268. Retrieved 2019/09/03.