1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Base Information

Chemical Name:1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol
CAS No.:1236156-38-9
Molecular Formula:C₂₁H₂₀F₂N₄O
Molecular Weight:382.413
Hs Code.:

Synonyms:1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Suppliers and Price of 1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

There total 5 articles about 1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.4%

: C₁₈H₁₈F₂N₄O

: 106-96-7
propargyl bromide

: 1236156-38-9
1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Guidance literature:: With potassium carbonate; potassium iodide; In acetonitrile; at 20 ℃;

Reference yield:

: 1262683-31-7
C₁₄H₁₄F₂N₄O*ClH

: 100-44-7
benzyl chloride

: 1236156-38-9
1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Guidance literature:: With potassium carbonate; potassium iodide; In acetonitrile; Reflux;
DOI:10.1016/j.cclet.2013.01.015

Reference yield:

: 86386-77-8
1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole methanesulfonate

: 1236156-38-9
1-(benzyl(prop-2-ynyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / ethanol / Reflux

2: potassium iodide; potassium carbonate / acetonitrile / Reflux

With potassium carbonate; triethylamine; potassium iodide; In ethanol; acetonitrile;
DOI:10.1016/j.cclet.2013.01.015