methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

Base Information

Chemical Name:methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate
CAS No.:871116-44-8
Molecular Formula:C₂₃H₃₁O₇P
Molecular Weight:450.469
Hs Code.:

Synonyms:methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

Suppliers and Price of methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

There total 6 articles about methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 871116-43-7
dimethyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

: 871116-44-8
methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

Guidance literature:: With TEA; thiophenol; In tetrahydrofuran; at 20 ℃; for 48h;
DOI:10.1002/ejoc.200500440

Reference yield:

: 871116-42-6
dimethyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-L-glycero-L-talo-heptit-1-yl phosphonate

: 871116-44-8
methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / Ag₂O / dimethylformamide / 72 h / 20 °C

2: 46 percent / TEA; thiophenol / tetrahydrofuran / 48 h / 20 °C

With TEA; thiophenol; silver(l) oxide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.200500440

Reference yield:

: 3,4-di-O-benzyl-2-O-p-methoxybenzyl-L-rhamnopyranose

: 871116-44-8
methyl 2,6-anhydro-1,7-dideoxy-4,5-di-O-benzyl-3-O-methyl-L-glycero-L-talo-heptit-1-yl phosphonate

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / NaH / 1,2-dimethoxy-ethane / 48 h / 20 °C

2: 0.74 g / DDQ / CH₂Cl₂; H₂O / 2 h / 20 °C

3: 70 percent / Ag₂O / dimethylformamide / 72 h / 20 °C

4: 46 percent / TEA; thiophenol / tetrahydrofuran / 48 h / 20 °C

With TEA; sodium hydride; thiophenol; 2,3-dicyano-5,6-dichloro-p-benzoquinone; silver(l) oxide; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.200500440