1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine

Base Information

Chemical Name:1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine
CAS No.:1020658-51-8
Molecular Formula:C₁₄H₁₃BrF₃N₃OS
Molecular Weight:408.242
Hs Code.:

Synonyms:1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine

Suppliers and Price of 1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine

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Technology Process of 1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine

There total 1 articles about 1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 916889-34-4
5-{4-[2-(trifluoromethyl)phenoxy]piperidin-1-yl}-1,3,4-thiadiazol-2-amine

: 1020658-51-8
1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine

Guidance literature:: 5-{4-[2-(trifluoromethyl)phenoxy]piperidin-1-yl}-1,3,4-thiadiazol-2-amine; With copper(ll) bromide; In acetonitrile; for 0.0833333h;

With tert.-butylnitrite; at 20 - 60 ℃; for 0.25h;

Reference yield:

: 916326-10-8
ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate

: 1020658-51-8
1-(5-bromo-1,3,4-thiadiazol-2-yl)-4-[2-(trifluoromethyl)phenoxy]piperidine

: 1020658-52-9
ethyl 5-[5-(4-{[2-(trifluoromethyl)phenyl]oxy}piperidin-1-yl)-1,3,4-thiadiazol-2-yl]pyridine-3-carboxylate

Guidance literature:: With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; N,N-dimethyl-formamide; at 80 ℃; for 5.08333h;