EU9DD7762T

Base Information

Chemical Name:EU9DD7762T
CAS No.:554429-88-8
Molecular Formula:C₃₉H₄₅NO₇
Molecular Weight:639.789
Hs Code.:
UNII:EU9DD7762T
ChEMBL ID:CHEMBL207362

Synonyms:CHEMBL207362;EU9DD7762T;RWJ443931;RWJ-443931;1,1'-((5R)-5,11-Dihydro-5-(4-(2-(1-piperidinyl)ethoxy)phenyl)(1)benzopyrano(4,3-C)(1)benzopyran-2,8-diyl) bis(2,2-dimethylpropanoate);554429-88-8;Bis(2,2-dimethylpropionic acid) 5(R)-(4-(2-(1-piperidinyl)ethoxy)phenyl)-5,11-dihydro-1-benzopyran(4,3-C)(1)benzopyran-2,8-diyl diester;Propanoic acid, 2,2-dimethyl-, 1,1'-((5R)-5,11-dihydro-5-(4-(2-(1-piperidinyl)ethoxy)phenyl)(1)benzopyrano(4,3-C)(1)benzopyran-2,8-diyl) ester;UNII-EU9DD7762T;SCHEMBL5116548;BDBM50187240;2,2-dimethyl-propionic acid (R)-8-(2,2-dimethyl-propionyloxy)-11-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-5,11-dihydro-chromeno[4,3-c]chromen-2-yl ester;2,2-Dimethyl-propionic acid (R)-8-(2,2-dimethyl-propionyloxy)-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-5,11-dihydro-chromeno[4,3-c]chromen-2-yl ester

Suppliers and Price of EU9DD7762T

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of EU9DD7762T

Chemical Property:

XLogP3:7.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:11
Exact Mass:639.31960277
Heavy Atom Count:47
Complexity:1120

Purity/Quality:: ≥98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C(=O)OC1=CC2=C(C=C1)C3=C(C(O2)C4=CC=C(C=C4)OCCN5CCCCC5)C6=C(C=C(C=C6)OC(=O)C(C)(C)C)OC3
Isomeric SMILES:CC(C)(C)C(=O)OC1=CC2=C(C=C1)C3=C([C@H](O2)C4=CC=C(C=C4)OCCN5CCCCC5)C6=C(C=C(C=C6)OC(=O)C(C)(C)C)OC3

Technology Process of EU9DD7762T

There total 11 articles about EU9DD7762T which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 554430-87-4
2,8-bis(tert-butyl-dimethyl-silyloxy)-11H-chromeno[4,3-c]chromen-5-one

: 554429-88-8
2,2-dimethyl-propionic acid 8-(2,2-dimethyl-propionyloxy)-5(R)-[4-(2-piperidin-1-yl-ethoxy)phenyl]-5,11-dihydro-chromeno[4,3-c]chromen-2-yl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: diisobutylaluminum hydride / toluene / 5 h / -78 °C

2.1: n-BuLi / tetrahydrofuran; pentane / 1 h / -78 °C

2.2: tetrahydrofuran; pentane / 1 h / -78 °C

3.1: aq. HCl / toluene / 0.5 h / 20 °C

4.1: tetra-n-butylammonium fluoride / tetrahydrofuran / 3 h

5.1: Et₃N / CH₂Cl₂ / 0 - 20 °C

6.1: chiral HPLC

With hydrogenchloride; n-butyllithium; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; triethylamine; In tetrahydrofuran; dichloromethane; toluene; pentane;
DOI:10.1021/jm060353u

Reference yield:

: 553681-47-3
2,8-bis(tert-butyl-dimethyl-silyloxy)-5,11-dihydro-chromeno[4,3-c]chromen-5-ol

: 554429-88-8
2,2-dimethyl-propionic acid 8-(2,2-dimethyl-propionyloxy)-5(R)-[4-(2-piperidin-1-yl-ethoxy)phenyl]-5,11-dihydro-chromeno[4,3-c]chromen-2-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-BuLi / tetrahydrofuran; pentane / 1 h / -78 °C

1.2: tetrahydrofuran; pentane / 1 h / -78 °C

2.1: aq. HCl / toluene / 0.5 h / 20 °C

3.1: tetra-n-butylammonium fluoride / tetrahydrofuran / 3 h

4.1: Et₃N / CH₂Cl₂ / 0 - 20 °C

5.1: chiral HPLC

With hydrogenchloride; n-butyllithium; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; dichloromethane; toluene; pentane;
DOI:10.1021/jm060353u

Reference yield:

: 554430-98-7
5-[4-(2-(piperidin-1-yl)ethoxy)phenyl]-5,11-dihydrochromeno[4,3-c]-chromene-2,8-diol

: 554429-88-8
2,2-dimethyl-propionic acid 8-(2,2-dimethyl-propionyloxy)-5(R)-[4-(2-piperidin-1-yl-ethoxy)phenyl]-5,11-dihydro-chromeno[4,3-c]chromen-2-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 0 - 20 °C

2: chiral HPLC

With triethylamine; In dichloromethane;
DOI:10.1021/jm060353u