(3R,4R)-3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one

Base Information Edit

Chemical Name:(3R,4R)-3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one
CAS No.:78473-71-9
Molecular Formula:C₁₈H₁₈O₄
Molecular Weight:298.339
Hs Code.:
European Community (EC) Number:634-756-3
DSSTox Substance ID:DTXSID0048183
Nikkaji Number:J454.067K
Wikipedia:Enterolactone
Wikidata:Q3055376
Metabolomics Workbench ID:78577
ChEMBL ID:CHEMBL471475
Mol file:78473-71-9.mol

Synonyms:2,3-BHBB;2,3-bis(3'-hydroxybenzyl)butyrolactone;2,3-bis(3'-hydroxybenzyl)butyrolactone, (trans)-(+-)-isomer;2,3-bis(3'-hydroxybenzyl)butyrolactone, (trans)-isomer;3,4-bis((3-hydroxyphenyl)methyl)dihydro-2-(3H)-furanone;BHMDF;enterolactone;HPMF;trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone

Suppliers and Price of (3R,4R)-3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Enterolactone ~95%(HPLC)
5 mg
$ 128.00

Sigma-Aldrich
Enterolactone ~95% (HPLC)
5mg-f
$ 124.00

Sigma-Aldrich
Enterolactone ~95%(HPLC)
1 mg
$ 42.00

Sigma-Aldrich
Enterolactone ~95% (HPLC)
1mg-f
$ 40.60

Sigma-Aldrich
(±)-Enterolactone analytical standard
10mg
$ 289.00

Cayman Chemical
(±)-Enterolactone ≥95%
50mg
$ 980.00

Cayman Chemical
(±)-Enterolactone ≥95%
10mg
$ 244.00

Cayman Chemical
(±)-Enterolactone ≥95%
5mg
$ 136.00

Cayman Chemical
(±)-Enterolactone ≥95%
1mg
$ 42.00

Cayman Chemical
(±)-Enterolactone ≥95%
500 μg
$ 28.00

Total 16 raw suppliers

Chemical Property of (3R,4R)-3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one Edit

Chemical Property:

Vapor Pressure:3.29E-13mmHg at 25°C
Melting Point:141-143°
Boiling Point:561.4°C at 760 mmHg
Flash Point:209°C
PSA：66.76000
Density:1.298±0.06 g/cm3 (20 ºC 760 Torr)
LogP:2.67220
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:298.12050905
Heavy Atom Count:22
Complexity:383

Purity/Quality:

98%,99%, ^*data from raw suppliers

Enterolactone ~95%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1C(C(C(=O)O1)CC2=CC(=CC=C2)O)CC3=CC(=CC=C3)O
Isomeric SMILES:C1[C@@H]([C@H](C(=O)O1)CC2=CC(=CC=C2)O)CC3=CC(=CC=C3)O
Uses A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer.

Technology Process of (3R,4R)-3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one

There total 88 articles about (3R,4R)-3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%