Technology Process of Methyl Nα,Nε-dibenzoyl-2-vinyllysinate
There total 11 articles about Methyl Nα,Nε-dibenzoyl-2-vinyllysinate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
aluminium amalgam;
In
tetrahydrofuran; water;
at 70 ℃;
for 4h;
DOI:10.1055/s-1980-29063
- Guidance literature:
-
Multi-step reaction with 8 steps
1: SO2Cl / 1 h / 40 °C
2: NEt3 / CH2Cl2 / 21 h / Ambient temperature
3: LDA / tetrahydrofuran / -78 °C
4: 3N HCl / tetrahydrofuran / 23 h / Ambient temperature
5: NEt3 / 15 h / Ambient temperature
6: 1.) sodium trimethoxyborohydride / 1.) DMF, 65 deg C, 1 h, 2.) DMF, 110 deg C, 1 h
8: 1.) O3, 2.) 1-hexene / 1.) CH2Cl2, -78 deg C, 2.) CCl4, reflux, 30 min
With
hydrogenchloride; 1-hexene; sulfuryl dichloride; sodium trimethoxyborohydride; ozone; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: LDA / tetrahydrofuran / -78 °C
2: 3N HCl / tetrahydrofuran / 23 h / Ambient temperature
3: NEt3 / 15 h / Ambient temperature
4: 1.) sodium trimethoxyborohydride / 1.) DMF, 65 deg C, 1 h, 2.) DMF, 110 deg C, 1 h
6: 1.) O3, 2.) 1-hexene / 1.) CH2Cl2, -78 deg C, 2.) CCl4, reflux, 30 min
With
hydrogenchloride; 1-hexene; sodium trimethoxyborohydride; ozone; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran;
