2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

Base Information

Chemical Name:2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester
CAS No.:1574531-86-4
Molecular Formula:C₂₁H₂₀BrN₃O₂
Molecular Weight:426.313
Hs Code.:

Synonyms:2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

Suppliers and Price of 2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

There total 4 articles about 2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 79670-17-0
methyl 2-bromomethyl-5-bromobenzoate

: 1539-42-0
bis[(2-pyridyl)methyl]amine

: 1574531-86-4
2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; for 7h; Reflux;
DOI:10.1021/ic402695c

Reference yield:

: 79669-50-4
methyl 2-methyl-5-bromobenzoate

: 1574531-86-4
2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide; dibenzoyl peroxide; tetrachloromethane

2: triethylamine / tetrahydrofuran / 7 h / Reflux

With tetrachloromethane; N-Bromosuccinimide; triethylamine; dibenzoyl peroxide; In tetrahydrofuran;
DOI:10.1021/ic402695c

Reference yield:

: 118-90-1
ortho-methylbenzoic acid

: 1574531-86-4
2-[(bis-pyridin-2-ylmethylamino)-methyl]-5-bromobenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: bromine; iron

2: sulfuric acid

3: N-Bromosuccinimide; dibenzoyl peroxide; tetrachloromethane

4: triethylamine / tetrahydrofuran / 7 h / Reflux

With tetrachloromethane; N-Bromosuccinimide; sulfuric acid; bromine; iron; triethylamine; dibenzoyl peroxide; In tetrahydrofuran;
DOI:10.1021/ic402695c