79669-50-4

Basic information

• Product Name: methyl 5-bromo-2-methyl-benzoate
• Synonyms: Methyl 5-bromo-o-toluate;Methyl 2-Methyl-5-Bromobenzoate;Methyl 5-bromo-2-methylbenzoate;5-bromo-2-methyl-benzoic acid methyl ester;methyl 5-bromo-2-met
• CAS NO: 79669-50-4
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07
• Mol File: 79669-50-4.mol
• Article Data: 34

Chemical Properties

• Melting Point: 46.0 to 50.0 °C
• Boiling Point: 265°C(lit.)
• Flash Point: 110.4 °C
• Appearance: Pale yellow/Powder
• Density: 1.433 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Soluble in water.
• CAS DataBase Reference: methyl 5-bromo-2-methyl-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-bromo-2-methyl-benzoate(79669-50-4)
• EPA Substance Registry System: methyl 5-bromo-2-methyl-benzoate(79669-50-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 79669-50-4(Hazardous Substances Data)

Usage

Uses

Methyl 5-bromo-2-methylbenzoate is used as a catalytic agent, petrochemical additive

Upstream product

• 67-56-1 methanol 
• 79669-49-1 5-bromo-2-methylbenzoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 118-90-1 ortho-methylbenzoic acid 
• 87-41-2 2-benzofuran-1(3H)-one 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 74-88-4 methyl iodide 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 77-78-1 dimethyl sulfate 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 578-22-3 2-methyl-5-hydroxybenzoic acid 
• 675109-26-9 6-bromo-1-oxo-2,3-dihydro-1H-isoindole 
• 79670-17-0 methyl 2-bromomethyl-5-bromobenzoate 
• 258886-04-3 (5-bromo-2-methylphenyl)methanol 
• 337536-14-8 methyl 3-bromo-2-(bromomethyl)benzoate 
• 371955-60-1 methyl 3-cyclopropyl-6-methylbenzoate 
• 1016163-89-5 methyl 5-bromo-2- formylbenzoate 
• 1265286-99-4 methyl 5-bromo-2-(dibromomethyl)-benzoate 
• 1265287-01-1 methyl 2-formyl-5-o-octylbenzoate 
• 1214328-43-4 2-methyl-5-(pyridin-3-yl)benzoic acid 
• 1630983-08-2 methyl 5-bromo-2-(difluoromethyl)benzoate 
• 1630983-13-9 2-(difluoromethyl)-5-(pyridin-3-yl)benzoic acid 

Relevant articles and documents

Compound containing benzo five-membered heterocyclic structure and preparation method and application thereof

The invention relates to the field of medicinal chemistry, and discloses a compound containing a benzo five-membered heterocyclic structure as well as a preparation method and application thereof. The invention also discloses a composition containing the benzo five-membered heterocyclic compound or the pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier, and application of the composition in preparation of PARP-1 and ERK inhibitors. The compound can be used for treating diseases such as tumors.

ISOINDOLINONE COMPOUNDS

Disclosed herein is a compound or pharmaceutically acceptable salts or stereoisomers thereof of of formula I wherein X1 is linear or branched C1-6 alkyl, C3-6 cycloalkyl, -C1-6 alkyl C3-6 cycloalkyl, C6-10 aryl, 5-10 membered heteroaryl, C1-6 alkyl C6-10 aryl, C1-6 alkyl 5-10 membered heteroaryl, wherein X1 is unsubstituted or substituted with one or more of halogen, linear or branched C1-6 alkyl, linear or branched C1-6 heteroalkyl, CF3, CHF2, -O-CHF2, -O-(CH2)2-OMe, OCF3, C1-6 alkylamino, -CN, -N(H)C(O)-C1- 6alkyl, -OC(O)-C1-6alkyl, -OC(O)-C1-4alkylamino, -C(O)O-C1-6alkyl, -COOH, - CHO, -C1-6alkylC(O)OH, -C1-6alkylC(O)O-C1-6alkyl, NH2, C1-6 alkoxy or C1-6 alkylhydroxy; X2 is hydrogen, C6-10 aryl, 5-10 membered heteroaryl, -O-(5-10 membered heteroaryl), 4-8 membered heterocycloalkyl, C1-4 alkyl 4-8 membered heterocycloalkyl, -O-(4-8 membered heterocycloalkyl), -O-C1-4 alkyl-(4-8 membered heterocycloalkyl), -OC(O)-C1-4alkyl-4-8 membered heterocycloalkyl or C6 aryloxy, wherein X2 is unsubstituted or substituted with one or more of linear or branched C1-6 alkyl, NH2, NMe2 or 5-6 membered heterocycloalkyl; n is 0, 1 or 2.

COMPOUNDS AND USES THEREOF

The present disclosure features compounds useful for the treatment of BAF complex-related disorders.