3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

Base Information

Chemical Name:3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol
CAS No.:68654-91-1
Molecular Formula:C₂₃H₃₈OSi
Molecular Weight:358.64
Hs Code.:

Synonyms:3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

Suppliers and Price of 3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

There total 9 articles about 3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 72867-87-9
3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenone

: 68654-91-1
3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at -20 ℃; for 1h;
DOI:10.1021/jo01295a019

Reference yield:

: 68654-84-2
4-pentynyl diethyl acetal

: 68654-91-1
3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

Guidance literature:: Multi-step reaction with 9 steps

1: 68 percent / n-BuLi / hexane; tetrahydrofuran / 1) -78 deg C, 1 h, 2) r.t., 18 h

2: 88 percent / HCl/H₂O / 3 h / Ambient temperature

3: 1) Mg

4: acetic acid / 12 h / 110 °C

5: 100 percent / LiAlH₄ / diethyl ether / 1.5 h / 0 °C

6: 98 percent / CrO₃/pyridine / CH₂Cl₂ / 0.33 h / Ambient temperature

7: C₆H₅Li

8: MeI / acetonitrile; H₂O / 19 h / 40 °C

9: 95 percent / LiAlH₄ / diethyl ether / 1 h / -20 °C

With pyridine; chromium(VI) oxide; hydrogenchloride; lithium aluminium tetrahydride; n-butyllithium; water; magnesium; phenyllithium; methyl iodide; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; water; acetic acid; acetonitrile;
DOI:10.1021/jo01295a019

Reference yield:

: 72867-79-9
4-Methyl-9-(trimethylsilyl)-trans-4-nonen-8-ynol

: 68654-91-1
3-Methyl-4-(7-methyl-12-(trimethylsilyl)-trans,trans-3,7-dodecadien-11-ynyl)-2-cyclohexenol

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / CrO₃/pyridine / CH₂Cl₂ / 0.33 h / Ambient temperature

2: C₆H₅Li

3: MeI / acetonitrile; H₂O / 19 h / 40 °C

4: 95 percent / LiAlH₄ / diethyl ether / 1 h / -20 °C

With pyridine; chromium(VI) oxide; lithium aluminium tetrahydride; phenyllithium; methyl iodide; In diethyl ether; dichloromethane; water; acetonitrile;
DOI:10.1021/jo01295a019