(Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

Base Information

Chemical Name:(Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate
CAS No.:934016-65-6
Molecular Formula:C₂₆H₃₈NO₆PS
Molecular Weight:523.631
Hs Code.:

Synonyms:(Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

Suppliers and Price of (Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

There total 1 articles about (Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 683-08-9
Diethyl methylphosphonate

: 620165-40-4
(S_S,S)-(+)-methyl N-(p-toluenesulfinyl)-3-amino-7-benzyloxyheptanoate

: 934016-65-6
(Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

Guidance literature:: Diethyl methylphosphonate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.75h;

(S_S,S)-(+)-methyl N-(p-toluenesulfinyl)-3-amino-7-benzyloxyheptanoate; In tetrahydrofuran; hexane; at -78 ℃; for 2h;
DOI:10.1021/jo062365t

Reference yield:

: 934016-65-6
(Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

: [6-(4-benzyloxy-butyl)-4-oxo-1,4,5,6-tetrahydro-pyridin-3-yl]-phosphonic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 12 h

2: aq. HCl / 1 h

With hydrogenchloride; In toluene;
DOI:10.1021/jo062365t

Reference yield:

: 934016-65-6
(Ss,S)-(+)-diethyl 8-(benzyloxy)-4-(4-methylphenylsulfinamido)-2-oxooctylphosphonate

: 934016-66-7
(S)-(+)-tert-butyl 2-(4-(benzyloxy)butyl)-5-(diethoxyphosphoryl)-4-oxo-3,4-dihydropyridine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 12 h

2: aq. HCl / 1 h

3: 1.63 g / Et₃N; DMAP / tetrahydrofuran / 3 h

With hydrogenchloride; dmap; triethylamine; In tetrahydrofuran; toluene;
DOI:10.1021/jo062365t