(3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde

Base Information

Chemical Name:(3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde
CAS No.:527744-26-9
Molecular Formula:C₁₆H₁₄F₂O₃S
Molecular Weight:324.348
Hs Code.:

Synonyms:(3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde

Chemical Property:

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Technology Process of (3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde

There total 2 articles about (3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 795310-67-7
(3R)-3-(3,5-difluorophenyl)-3-[4-(methylsulfonyl)phenyl]propan-1-ol

: 527744-26-9
(3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde

Guidance literature:: With Dess-Martin periodane; In dichloromethane; for 0.75h;

Reference yield:

: 527744-26-9
(3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde

Guidance literature:

Reference yield: 50.0%

: 527744-26-9
(3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde

: 4-[2-(4-methanesulphonylphenylsulphonyl)ethyl]piperidine hydrochloride

: 718610-20-9
1-{(3R)-3-(3,5-difluorophenyl)-3-[4-(methylsulfonyl)phenyl]propyl}-4-(2-{[4-(methylsulfonyl)phenyl]sulfonyl}ethyl)piperidine

Guidance literature:: (3R)-3-(3,5-difluorophenyl)-3-(4-methanesulphonylphenyl)-propionaldehyde; 4-[2-(4-methanesulphonylphenylsulphonyl)ethyl]piperidine hydrochloride; In dichloromethane; at 20 ℃; for 0.5h;

With sodium tris(acetoxy)borohydride; In dichloromethane; for 1h;