Oxyphenbutazone

Base Information

Chemical Name:Oxyphenbutazone
CAS No.:129-20-4
Molecular Formula:C19H20 N2 O3
Molecular Weight:324.379
Hs Code.:2933990090
European Community (EC) Number:204-936-2
NSC Number:757261,526053
UNII:A7D84513GV
DSSTox Substance ID:DTXSID1045291
Nikkaji Number:J10.648H
Wikipedia:Oxyphenbutazone
Wikidata:Q4116192
NCI Thesaurus Code:C74597
Pharos Ligand ID:1DWFZAZT8U1H
Metabolomics Workbench ID:122956
ChEMBL ID:CHEMBL1228
Mol file:129-20-4.mol

Synonyms:Diflamil;Hydroxyphenylbutazone;Oxyphenbutazone;Oxyphenylbutazone;Tanderil

Suppliers and Price of Oxyphenbutazone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Oxyphenbutazone
500ul
$ 360.00

Usbiological
Oxyphenbutazone
500ul
$ 306.00

TRC
Oxyphenbutazone
25mg
$ 160.00

Sigma-Aldrich
Oxyphenbutazone ≥98% (HPLC)
10mg
$ 118.00

Sigma-Aldrich
Oxyphenbutazone ≥98% (HPLC)
50mg
$ 452.00

ChemScene
Oxyphenbutazone ≥99.0%
50mg
$ 600.00

ChemScene
Oxyphenbutazone ≥99.0%
10mg
$ 230.00

ChemScene
Oxyphenbutazone ≥99.0%
25mg
$ 365.00

Cayman Chemical
Oxyphenbutazone ≥98%
10mg
$ 88.00

Cayman Chemical
Oxyphenbutazone ≥98%
5mg
$ 56.00

Total 30 raw suppliers

Chemical Property of Oxyphenbutazone

Chemical Property:

Vapor Pressure:4.7E-10mmHg at 25°C
Melting Point:109-111°C
Refractive Index:1.6140 (estimate)
Boiling Point:485.6°Cat760mmHg
PKA:pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
Flash Point:247.5°C
PSA：60.85000
Density:1.241g/cm³
LogP:3.62340
Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility.:DMSO: soluble10mg/mL, clear
Water Solubility.:20mg/L(room temperature)
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:324.14739250
Heavy Atom Count:24
Complexity:454

Purity/Quality:

97% ^*data from raw suppliers

Oxyphenbutazone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,N
Hazard Codes:Xn,N
Statements: 22-50
Safety Statements: 61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3
Recent ClinicalTrials:The UPDATE Trial (Uvb Phototherapy in Dermatology for ATopic Eczema)
Uses Anti-inflammatory;Cyclooxygenase inhibito
Indications Oxyphenbutazone (Oxalid, Tandearil) is the principal uricosuric metabolite of phenylbutazone. It has the same indications and toxicities as phenylbutazone.
Therapeutic Function Antiinflammatory

Technology Process of Oxyphenbutazone

There total 10 articles about Oxyphenbutazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133-08-4
diethyl butylmalonate

: 129-20-4
OXYPHENBUTAZONE

Guidance literature:: Multi-step reaction with 2 steps

1: sodium ethylate; xylene

2: Raney nickel; aq.-ethanolic NaOH / Hydrogenation

With sodium hydroxide; sodium ethanolate; nickel; xylene;
DOI:10.1002/hlca.19570400218