tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate)

Base Information

• Chemical Name: tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate)
• CAS No.: 856134-28-6
• Molecular Formula: C₆₄H₈₆Br₂N₆O₉
• Molecular Weight: 1243.23
• Mol file: 856134-28-6.mol

Synonyms:tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate)

Chemical Property of tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate)

There total 1 articles about tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-6-bromomethyl-2-pyridylmethylenenitrilobis(acetic acid) di(tert-butyl ester) (178321-70-5) + 6-(4-methoxytrityl)hexanediamine → tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate) (856134-28-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 2h;

Reference yield: 90.0%

tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate) (856134-28-6) + (2,4,6-trimethoxyphenyl)boronic acid (135159-25-0) → tetra(tertbutyl) 2,2',2,2'''-{[6-N-(4-methoxytrityl)aminohexyl-imino]bis(methylene)bis[4-(2,4,6-trimethoxyphenyl)pyridine-6,2-diyl]bis(methylenenitrilo)}tetrakis(acetate) (856132-23-5)

Guidance literature:

With caesium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In DMF (N,N-dimethyl-formamide); at 95 ℃;

Reference yield: 75.0%

tetra(tert-butyl) 2,2',2,2'-{[6-N-(4-methoxytrityl)hexylimino]bis(methylene)bis-(4-bromopyridine-6,2-diyl)bis(methylenenitrilo)}tetrakis(acetate) (856134-28-6) + 2-(tributylstannyl)furan (118486-94-5) → 2,2',2'',2'''-([6-(4-methoxy)tritylaminohexyl]bis(methylene)bis[(4-(2-furyl)pyridine-6,2-diyl)]bis(methylenenitrilo))tetrakis(acetic acid) tetra(tert-butyl ester) (847454-08-4)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In DMF (N,N-dimethyl-formamide); at 90 ℃; for 2.5h;

upstream raw materials:

4-bromo-6-bromomethyl-2-pyridylmethylenenitrilobis(acetic acid) di(tert-butyl ester)

Downstream raw materials:

2,2',2'',2'''-([6-(4-methoxy)tritylaminohexyl]bis(methylene)bis[(4-(2-furyl)pyridine-6,2-diyl)]bis(methylenenitrilo))tetrakis(acetic acid) tetra(tert-butyl ester)

tetra(tertbutyl) 2,2',2,2'''-{[6-N-(4-methoxytrityl)aminohexyl-imino]bis(methylene)bis[4-(2,4,6-trimethoxyphenyl)pyridine-6,2-diyl]bis(methylenenitrilo)}tetrakis(acetate)