4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-(phenylmethyl)benzeneethanamine

Base Information

Chemical Name:4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-(phenylmethyl)benzeneethanamine
CAS No.:226992-15-0
Molecular Formula:C₂₃H₂₇N₃O
Molecular Weight:361.487
Hs Code.:
DSSTox Substance ID:DTXSID901158019

Synonyms:DTXSID901158019;4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-(phenylmethyl)benzeneethanamine;226992-15-0

Suppliers and Price of 4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-(phenylmethyl)benzeneethanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-(phenylmethyl)benzeneethanamine

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:361.215412493
Heavy Atom Count:27
Complexity:383

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN(CCC2=CC=C(C=C2)N)CCOC3=CC=C(C=C3)N

Technology Process of 4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-(phenylmethyl)benzeneethanamine

There total 7 articles about 4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-(phenylmethyl)benzeneethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 226992-14-9
N-benzyl-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine

: 226992-15-0
N-benzyl-N-[2-(p-aminophenoxy)ethyl]-p-(amino)phenethylamine

Guidance literature:: With hydrogenchloride; ammonium chloride; iron; In acetone; at 45 ℃;
DOI:10.1021/jm010574u

Reference yield:

: 6270-07-1
N-<2-(4-nitrophenyl)ethyl>acetamide

: 226992-15-0
N-benzyl-N-[2-(p-aminophenoxy)ethyl]-p-(amino)phenethylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / 47percent HBr / 6 h / Heating

2: 81.5 percent / K₂CO₃ / acetonitrile / 20 °C

3: 61 percent / K₂CO₃ / acetonitrile / 3.5 h / Heating

4: 87 percent / aq. HCl; iron; ammonium chloride / acetone / 45 °C

With hydrogenchloride; ammonium chloride; iron; potassium carbonate; In acetone; acetonitrile;
DOI:10.1021/jm010574u

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 226992-15-0
N-benzyl-N-[2-(p-aminophenoxy)ethyl]-p-(amino)phenethylamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: NaOH; TBA / ethanol / 0.25 h / Heating

1.2: 46.8 percent / ethanol / 24 h / Heating

2.1: 81.5 percent / K₂CO₃ / acetonitrile / 20 °C

3.1: 61 percent / K₂CO₃ / acetonitrile / 3.5 h / Heating

4.1: 87 percent / aq. HCl; iron; ammonium chloride / acetone / 45 °C

With hydrogenchloride; sodium hydroxide; ammonium chloride; iron; potassium carbonate; tert-butylamine; In ethanol; acetone; acetonitrile;
DOI:10.1021/jm010574u