2-ethyl-1-phenylbutanol

Base Information

• Chemical Name: 2-ethyl-1-phenylbutanol
• CAS No.: 854179-62-7
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.274
• Mol file: 854179-62-7.mol

Synonyms:2-ethyl-1-phenylbutanol

Chemical Property of 2-ethyl-1-phenylbutanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-ethyl-1-phenylbutanol

There total 3 articles about 2-ethyl-1-phenylbutanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

2-Ethylbutyraldehyde (97-96-1) + iodobenzene (591-50-4) → 2-ethyl-1-phenylbutanol (854179-62-7)

Guidance literature:

With diphenyl hydrogen phosphate; [Ni(dipy)(μ-Cl)2]; diisopropylamine; sodium iodide; zinc; In hexane; at 95 ℃; for 7h; Inert atmosphere; Sealed tube;

DOI:10.1002/ejoc.201901367

Reference yield:

2-Ethylbutyrophenon (5682-46-2) → 2-ethyl-1-phenylbutanol (854179-62-7)

Guidance literature:

With potassium hydroxide; In isopropyl alcohol; at 130 ℃;

Reference yield:

2-Ethylbutyraldehyde (97-96-1) + phenylmagnesium bromide → 2-ethyl-1-phenylbutanol (854179-62-7)

Guidance literature:

With diethyl ether;

DOI:10.1021/ja01115a050

upstream raw materials:

2-Ethylbutyraldehyde

2-Ethylbutyrophenon

iodobenzene

Downstream raw materials:

2-ethyl-1-phenyl-butan-1-one oxime

2-Ethylbutyrophenon

(2-ethylbut-1-en-1-yl)benzene

Refernces