TL 350

Base Information

Chemical Name:TL 350
CAS No.:94270-93-6
Molecular Formula:C₁₆H₂₄N₂O
Molecular Weight:260.379
Hs Code.:
Mol file:94270-93-6.mol

Synonyms:TL 350

Suppliers and Price of TL 350

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of TL 350

Chemical Property:

Vapor Pressure:2.04E-08mmHg at 25°C
Melting Point:139 - 140.5 °C (benzene)
Boiling Point:441.7°Cat760mmHg
Flash Point:221°C
PSA：39.26000
Density:1.087g/cm³
LogP:3.53800

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of TL 350

There total 30 articles about TL 350 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 131475-26-8
4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

: 94270-93-6
4-<2-(dipropylamino)ethyl>-6-hydroxyimidole

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 1h; under 760 Torr;

Reference yield:

: 52090-24-1
methyl 2-methyl-3,5-dinitrobenzoate

: 94270-93-6
4-<2-(dipropylamino)ethyl>-6-hydroxyimidole

Guidance literature:: Multi-step reaction with 15 steps

1: 60 percent / HCO₂NHEt₃ / 5percent Pd/C / acetonitrile / Heating

2: 70 percent / 48percent HBF₄, tert-butyl nitrite / ethanol / 0.5 h / 0 °C

3: Cu(NO₃)2*3H₂O, Cu₂O, 0.1 N H₂SO₄ / 0.25 h

4: 95 percent / K₂CO₃ / acetone / 3.5 h / Ambient temperature

5: 61 percent / dimethylformamide / 0.67 h / 115 °C

6: 50 percent / H₂ / 5percent Pd/C / benzene / 3 h

7: K₂CO₃ / acetone / 4 h / Ambient temperature

8: LiAlH₄ / tetrahydrofuran / 0 °C

9: 84 percent / MnO₂ / CH₂Cl₂ / 2 h

10: 1.) n-BuLi / 1.) THF, hexane, RT, 0.5 h, 2.) THF, hexane, RT, 0.75 h

11: NaOH, tetra-n-butylammonium bisulfate / CH₂Cl₂

12: Hg(OAc)2 / benzene / 5 h / 45 °C

13: NaCNBH₃, AcOH / acetonitrile / 0.17 h / pH 7

14: n-BuLi / benzene; hexane / 0.07 h / 10 °C

15: AcOH / benzene; hexane

With copper(I) oxide; manganese(IV) oxide; sodium hydroxide; lithium aluminium tetrahydride; tetrafluoroboric acid; n-butyllithium; tert.-butylnitrite; sulfuric acid; mercury(II) diacetate; hydrogen; tetra(n-butyl)ammonium hydrogensulfate; triethylammonium formate; sodium cyanoborohydride; potassium carbonate; copper(II) nitrate; acetic acid; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; acetonitrile; benzene;
DOI:10.1021/jm00369a026

Reference yield:

: 88132-51-8
methyl 5-hydroxy-2-methyl-3-nitrobenzoate

: 94270-93-6
4-<2-(dipropylamino)ethyl>-6-hydroxyimidole

Guidance literature:: Multi-step reaction with 12 steps

1: 95 percent / K₂CO₃ / acetone / 3.5 h / Ambient temperature

2: 61 percent / dimethylformamide / 0.67 h / 115 °C

3: 50 percent / H₂ / 5percent Pd/C / benzene / 3 h

4: K₂CO₃ / acetone / 4 h / Ambient temperature

5: LiAlH₄ / tetrahydrofuran / 0 °C

6: 84 percent / MnO₂ / CH₂Cl₂ / 2 h

7: 1.) n-BuLi / 1.) THF, hexane, RT, 0.5 h, 2.) THF, hexane, RT, 0.75 h

8: NaOH, tetra-n-butylammonium bisulfate / CH₂Cl₂

9: Hg(OAc)2 / benzene / 5 h / 45 °C

10: NaCNBH₃, AcOH / acetonitrile / 0.17 h / pH 7

11: n-BuLi / benzene; hexane / 0.07 h / 10 °C

12: AcOH / benzene; hexane

With manganese(IV) oxide; sodium hydroxide; lithium aluminium tetrahydride; n-butyllithium; mercury(II) diacetate; hydrogen; tetra(n-butyl)ammonium hydrogensulfate; sodium cyanoborohydride; potassium carbonate; acetic acid; palladium on activated charcoal; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; acetonitrile; benzene;
DOI:10.1021/jm00369a026