2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate

Base Information

Chemical Name:2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate
CAS No.:359880-09-4
Molecular Formula:C₂H₂O₄*C₂₅H₃₁ClN₂O
Molecular Weight:501.022
Hs Code.:

Synonyms:2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate

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Chemical Property of 2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate

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Technology Process of 2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate

There total 3 articles about 2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 359880-05-0
1-cyclobutyl-4-oxo-piperidine

: 359880-09-4
2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium cyanoborohydride; acetic acid / methanol / 24 h / pH ~ 5

1.2: pH ~ 10

2.1: dichloromethane / 5 h

3.1: n-heptane; dichloromethane

With sodium cyanoborohydride; acetic acid; In methanol; n-heptane; dichloromethane;

Reference yield:

: 359880-00-5
2-(4-Chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide

: 144-62-7,97993-78-7
oxalic acid

: 359880-09-4
2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate

Guidance literature:: In n-heptane; dichloromethane;

Reference yield:

: 359880-07-2
4-(4-methylbenzylamino)-1-cyclobutylpiperidine

: 359880-09-4
2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-cyclobutylpiperidin-4-yl)-acetamide oxalate

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 5 h

2: n-heptane; dichloromethane

In n-heptane; dichloromethane;